Vat blue 6 - 130-20-1
Vat blue 6
Catalog Number: BT-285798
CAS Number: 130-20-1
Molecular Formula: C28H12Cl2N2O4
Molecular Weight: 511.3 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
Vat blue 6 is a synthetic dye that belongs to the class of vat dyes. It is commonly used in the textile industry for dyeing cotton, wool, and silk. The dye is also used in medical and environmental research due to its unique chemical structure and biological activity.
Properties
CAS Number
130-20-1
Product Name
Vat blue 6
IUPAC Name
15,30-dichloro-2,17-diazaheptacyclo[16.12.0.03,16.04,13.06,11.019,28.021,26]triaconta-1(30),3,6,8,10,13,15,18,21,23,25,28-dodecaene-5,12,20,27-tetrone
Molecular Formula
C28H12Cl2N2O4
Molecular Weight
511.3 g/mol
InChI
InChI=1S/C28H12Cl2N2O4/c29-17-9-15-19(27(35)13-7-3-1-5-11(13)25(15)33)23-21(17)32-24-20-16(10-18(30)22(24)31-23)26(34)12-6-2-4-8-14(12)28(20)36/h1-10,31-32H
InChI Key
UGCDBQWJXSAYIL-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(=O)C3=CC(=C4C(=C3C2=O)NC5=C(C=C6C(=C5N4)C(=O)C7=CC=CC=C7C6=O)Cl)Cl
Solubility
Soluble in DMSO
Synonyms
Vat Blue 6; NSC 74700; NSC-74700; NSC74700
Canonical SMILES
C1=CC=C2C(=C1)C(=O)C3=CC(=C4C(=C3C2=O)NC5=C(C=C6C(=C5N4)C(=O)C7=CC=CC=C7C6=O)Cl)Cl
Method of Synthesis or Extraction
Vat blue 6 is synthesized through a complex process that involves several steps. The most commonly used method for its synthesis is the reduction of vat blue 4 using sodium dithionite. The yield of this method is high, and the efficiency is excellent. However, the process requires the use of toxic chemicals, which can pose a risk to the environment and human health. Other methods of synthesis include the use of zinc dust and sodium borohydride, which are less toxic but have lower yields.
Chemical Structure and Biological Activity
Vat blue 6 has a complex chemical structure that consists of a fused ring system of indigo and anthraquinone. The dye has a high affinity for cellulose fibers, making it an ideal dye for cotton fabrics. Vat blue 6 has been shown to have potent antioxidant and anti-inflammatory properties. It also exhibits antimicrobial activity against a wide range of bacteria and fungi.
Biological Effects
Vat blue 6 has been shown to have a significant impact on cell function and signal transduction. It has been found to inhibit the production of reactive oxygen species (ROS) and reduce oxidative stress in cells. The dye has also been shown to modulate the activity of several signaling pathways, including the NF-κB and MAPK pathways. Vat blue 6 has potential therapeutic effects in the treatment of inflammatory diseases, such as rheumatoid arthritis and psoriasis. However, the dye can also have toxic effects on cells at high concentrations.
Applications
In medical research, vat blue 6 has been used in drug development and clinical trials. The dye has been shown to have potential therapeutic effects in the treatment of inflammatory diseases and cancer. In environmental research, vat blue 6 has been used to study its effects on ecosystems and its role in pollution management. The dye has also been used in industrial research to improve product quality and efficiency. However, the use of vat blue 6 in manufacturing processes can pose health and safety risks to workers.
Future Perspectives and Challenges
The use of vat blue 6 in scientific research is limited by its toxicity and potential environmental impact. Future research should focus on developing safer and more sustainable methods of synthesis and exploring the full range of biological activities of the dye. The development of vat blue 6-based drugs and therapies could have significant implications for the treatment of inflammatory diseases and cancer. However, further research is needed to fully understand the potential therapeutic and toxic effects of the dye.
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