Home > Products > Bioactive Reagents P462 > 3'-O-(t-butyldimethylsilyl)thymidine

3'-O-(t-butyldimethylsilyl)thymidine

Catalog Number: EVT-316794

CAS Number: 40733-27-5

Molecular Formula: C16H28N2O5Si

Molecular Weight: 356.49 g/mol

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Product Introduction

Description

3'-O-(t-butyldimethylsilyl)thymidine, also known as TBS-thymidine, is a modified form of thymidine that is commonly used in scientific research. It is a nucleoside analog that has been modified to improve its stability and bioavailability. TBS-thymidine has been used in a variety of applications, including drug development, environmental research, and industrial manufacturing. In this paper, we will explore the synthesis and extraction methods of TBS-thymidine, its chemical structure and biological activity, its effects on cell function and signal transduction, its potential therapeutic and toxic effects, and its applications in various fields. We will also discuss the future perspectives and challenges of using TBS-thymidine in scientific research.

Properties

CAS Number

40733-27-5

Product Name

3'-O-(t-butyldimethylsilyl)thymidine

IUPAC Name

1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Molecular Formula

C16H28N2O5Si

Molecular Weight

356.49 g/mol

InChI

InChI=1S/C16H28N2O5Si/c1-10-8-18(15(21)17-14(10)20)13-7-11(12(9-19)22-13)23-24(5,6)16(2,3)4/h8,11-13,19H,7,9H2,1-6H3,(H,17,20,21)/t11-,12+,13+/m0/s1

InChI Key

QAPSNMNOIOSXSQ-YNEHKIRRSA-N

SMILES

CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O[Si](C)(C)C(C)(C)C

Canonical SMILES

CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O[Si](C)(C)C(C)(C)C

Isomeric SMILES

CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O[Si](C)(C)C(C)(C)C

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