1-Naphthalenesulfonic acid - 85-47-2
1-Naphthalenesulfonic acid
Catalog Number: BT-460216
CAS Number: 85-47-2
Molecular Formula: C10H8O3S
Molecular Weight: 208.24 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.
Product Introduction
Description
1-Naphthalenesulfonic acid is an organic compound with the chemical formula C10H8O3S. It is a white crystalline solid that is soluble in water and commonly used in various industrial and scientific applications. This paper aims to provide an overview of the synthesis, biological activity, and applications of 1-naphthalenesulfonic acid.
Properties
CAS Number
85-47-2
Product Name
1-Naphthalenesulfonic acid
IUPAC Name
naphthalene-1-sulfonic acid
Molecular Formula
C10H8O3S
Molecular Weight
208.24 g/mol
InChI
InChI=1S/C10H8O3S/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H,11,12,13)
InChI Key
PSZYNBSKGUBXEH-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)O
Synonyms
1-naphthalenemonosulfonate
1-naphthalenesulfonic acid
Canonical SMILES
C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)O
Method of Synthesis or Extraction
1-Naphthalenesulfonic acid can be synthesized through various methods, including sulfonation of naphthalene with sulfuric acid or oleum, oxidation of 1-naphthol with potassium permanganate, and reaction of naphthalene with chlorosulfonic acid. The efficiency and yield of each method depend on the reaction conditions, such as temperature, concentration, and reaction time. However, the sulfonation of naphthalene with sulfuric acid is the most commonly used method due to its high yield and low cost. Environmental and safety considerations should be taken into account during the synthesis process, as the reaction may produce toxic gases and waste.
Chemical Structure and Biological Activity
1-Naphthalenesulfonic acid has a sulfonic acid group (-SO3H) attached to the naphthalene ring. It is a strong acid and can dissociate in water to form the corresponding anion, which has various biological activities. The mechanism of action and biological targets of 1-naphthalenesulfonic acid depend on the specific application. For example, it can act as a surfactant and emulsifier in the detergent industry, as a catalyst in organic synthesis, and as a pH indicator in analytical chemistry. In addition, 1-naphthalenesulfonic acid and its derivatives have been reported to exhibit antimicrobial, anti-inflammatory, and anticancer activities.
Biological Effects
The biological effects of 1-naphthalenesulfonic acid on cell function and signal transduction depend on the concentration and exposure time. At low concentrations, it can stimulate cell proliferation and differentiation, while at high concentrations, it can induce cell death and apoptosis. The potential therapeutic and toxic effects of 1-naphthalenesulfonic acid should be carefully evaluated in preclinical and clinical studies before its application in medical research.
Applications
1-Naphthalenesulfonic acid has various applications in medical, environmental, and industrial research. In medical research, it can be used as a starting material for the synthesis of drugs and as a pH regulator in clinical trials. However, its potential side effects and toxicity should be considered in drug development. In environmental research, 1-naphthalenesulfonic acid can be used as a tracer for pollution management and as a surfactant in oil spill cleanup. Its sustainability and environmental impact should be evaluated in the context of the specific ecosystem. In industrial research, 1-naphthalenesulfonic acid can be used as a catalyst in chemical reactions and as a dye in textile manufacturing. Health and safety considerations should be taken into account during the production and use of 1-naphthalenesulfonic acid.
Future Perspectives and Challenges
The current limitations in the use and study of 1-naphthalenesulfonic acid include its potential toxicity, low solubility, and limited bioavailability. Possible solutions and improvements include the development of novel derivatives with improved pharmacokinetic properties and the optimization of the synthesis process to reduce waste and environmental impact. Future trends and prospects in the application of 1-naphthalenesulfonic acid in scientific research include its potential use as a drug delivery system and as a biosensor for disease diagnosis.
Conclusion:
1-Naphthalenesulfonic acid is a versatile compound with various applications in medical, environmental, and industrial research. Its synthesis, biological activity, and applications have been discussed in this paper. Further research is needed to fully understand its potential therapeutic and toxic effects and to develop novel derivatives with improved properties.
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