4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid, also known as Sudan I, is a synthetic organic compound that belongs to the azo dye family. It is commonly used as a coloring agent in various industries, including food, textiles, and plastics. However, it has been found to have potential health hazards, including carcinogenicity and genotoxicity.
Applications in Various Fields
In medical research, 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has been used as a model compound for studying the genotoxic and carcinogenic effects of azo dyes. It has also been investigated for its potential role in drug development, as it can bind to proteins and enzymes involved in disease pathways. In clinical trials, 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has not been used as a therapeutic agent due to its potential health hazards. In environmental research, 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has been found to have toxic effects on aquatic organisms and can accumulate in the food chain. It has also been used as a marker for pollution management, as it can be detected in wastewater and soil samples. In industrial research, 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has been used as a coloring agent in various products, but its use has been restricted due to its potential health hazards. It can also be used in manufacturing processes to improve product quality and efficiency, but health and safety considerations should be taken into account.
4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I can be synthesized by the diazotization of 4-amino-1-naphthol-3-sulfonic acid followed by coupling with aniline. The yield of this method is around 60-70%, and it requires the use of hazardous chemicals such as sodium nitrite and hydrochloric acid. Another method involves the reaction of 4-nitro-1-naphthol with aniline in the presence of sulfuric acid, followed by reduction with zinc dust. This method has a higher yield of around 80-90%, but it also involves the use of hazardous chemicals and generates toxic waste. Extraction of 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I from commercial products can be done using organic solvents such as methanol or acetone, but this method is not efficient and may not yield pure 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I. Environmental and safety considerations should be taken into account when using these methods, and proper disposal of hazardous waste should be ensured.
Chemical Structure and Biological Activity
4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has a chemical formula of C16H12N2O3S and a molecular weight of 308.34 g/mol. It has a naphthalene backbone with a phenylamino group and a sulfonic acid group attached to it. 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has been found to have potential carcinogenic and genotoxic effects, as it can bind to DNA and cause mutations. It has also been shown to induce oxidative stress and inflammation in cells.
Biological Effects
4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I can affect cell function and signal transduction by inducing DNA damage and oxidative stress. It has been shown to activate the NF-κB pathway, which is involved in inflammation and cell survival. 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I has also been found to inhibit the activity of topoisomerase II, an enzyme involved in DNA replication and repair. These effects can lead to potential therapeutic and toxic effects, depending on the dose and exposure.
Future Perspectives and Challenges
The use and study of 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I face several limitations, including its potential health hazards, limited availability of pure samples, and lack of standardized methods for detection and analysis. Possible solutions and improvements include the development of safer and more efficient synthesis and extraction methods, the use of alternative coloring agents in industries, and the implementation of stricter regulations on the use of 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I. Future trends and prospects in the application of 4-Hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid I in scientific research include the investigation of its role in disease pathways and the development of safer and more effective therapeutic agents.
Product FAQ
Q1: How Can I Obtain a Quote for a Product I'm Interested In?
To receive a quotation, send us an inquiry about the desired product.
The quote will cover pack size options, pricing, and availability details.
If applicable, estimated lead times for custom synthesis or sourcing will be provided.
Quotations are valid for 30 days, unless specified otherwise.
Q2: What Are the Payment Terms for Ordering Products?
New customers generally require full prepayment.
NET 30 payment terms can be arranged for customers with established credit.
Contact our customer service to set up a credit account for NET 30 terms.
We accept purchase orders (POs) from universities, research institutions, and government agencies.
Q3: Which Payment Methods Are Accepted?
Preferred methods include bank transfers (ACH/wire) and credit cards.
Request a proforma invoice for bank transfer details.
For credit card payments, ask sales representatives for a secure payment link.
Checks aren't accepted as prepayment, but they can be used for post-payment on NET 30 orders.
Q4: How Do I Place and Confirm an Order?
Orders are confirmed upon receiving official order requests.
Provide full prepayment or submit purchase orders for credit account customers.
Send purchase orders to sales@EVITACHEM.com.
A confirmation email with estimated shipping date follows processing.
Q5: What's the Shipping and Delivery Process Like?
Our standard shipping partner is FedEx (Standard Overnight, 2Day, FedEx International Priority), unless otherwise agreed.
You can use your FedEx account; specify this on the purchase order or inform customer service.
Customers are responsible for customs duties and taxes on international shipments.
Q6: How Can I Get Assistance During the Ordering Process?
Reach out to our customer service representatives at sales@EVITACHEM.com.
For ongoing order updates or questions, continue using the same email.
Remember, we're here to help! Feel free to contact us for any queries or further assistance.
Quick Inquiry
Note: Kindly utilize formal channels such as professional, corporate, academic emails, etc., for inquiries. The use of personal email for inquiries is not advised.
1-Decanamine, N,N-didecyl-, also known as DDAB, is a quaternary ammonium compound that is commonly used as a surfactant and emulsifier in various industries. DDAB has a long hydrophobic tail and a positively charged head, which makes it an effective agent for stabilizing emulsions and suspensions. In addition to its industrial applications, DDAB has also been studied for its biological activity, including its potential as a therapeutic agent.
1,1,1,3-Tetrachloropropane (TCP) is a synthetic organic compound that has been used in various industrial applications, including as a solvent, degreaser, and chemical intermediate. TCP is a highly toxic and persistent environmental pollutant that poses a significant risk to human health and the environment. This paper aims to provide an overview of the synthesis, biological activity, and applications of TCP.
2,6-Difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, also known as DFHBP, is a pyridine derivative that has gained significant attention in the scientific community due to its potential therapeutic and industrial applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of DFHBP.
2-(Methylthio)phenol, also known as 2-methylthiophenol or 2-methyl-4-(methylthio)phenol, is an organic compound with the chemical formula C8H10S. It is a colorless to pale yellow liquid with a strong, pungent odor. 2-(Methylthio)phenol is commonly used in the fragrance industry as a component of perfumes and other scented products. It is also used in the synthesis of other organic compounds and has potential applications in medical, environmental, and industrial research.
4,4'-Bis[N-(1-naphthyl)-N-phenylamino]-4''-phenyltriphenylamine, commonly known as NPB, is a highly efficient organic semiconductor material that has gained significant attention in recent years due to its potential applications in various fields, including medical, environmental, and industrial research. This paper aims to provide a comprehensive overview of NPB, including its method of synthesis, chemical structure, biological activity, potential therapeutic and toxic effects, applications in different research fields, future perspectives, and challenges.
2-Benzyloxybenzyl acetate is an organic compound with the chemical formula C16H14O3. It is commonly used in medical, environmental, and industrial research due to its unique chemical structure and biological activity.
4-Fluoro-2-methoxy-5-nitroaniline is a chemical compound that belongs to the class of nitroanilines. It is a yellow crystalline solid that is used in various fields such as medical research, environmental research, and industrial research. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, biological effects, applications, future perspectives, and challenges of 4-Fluoro-2-methoxy-5-nitroaniline.