Home > Products > Inhibitors/Agonists P275 > D-3263 (hydrochloride)

D-3263 (hydrochloride)

Catalog Number: EVT-253014

CAS Number: 1008763-54-9

Molecular Formula: C21H32ClN3O3

Molecular Weight: 409.95

The product is for non-human research only. Not for therapeutic or veterinary use.

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Product Introduction

Description

D-3263 hydrochloride is an orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].

Properties

CAS Number

1008763-54-9

Product Name

D-3263 (hydrochloride)

IUPAC Name

3-(2-aminoethyl)-5-methoxy-1-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexanecarbonyl]benzimidazol-2-one;hydrochloride

Molecular Formula

C21H32ClN3O3

Molecular Weight

409.95

InChI

InChI=1S/C21H31N3O3.ClH/c1-13(2)16-7-5-14(3)11-17(16)20(25)24-18-8-6-15(27-4)12-19(18)23(10-9-22)21(24)26;/h6,8,12-14,16-17H,5,7,9-11,22H2,1-4H3;1H/t14-,16+,17-;/m1./s1

SMILES

CC1CCC(C(C1)C(=O)N2C3=C(C=C(C=C3)OC)N(C2=O)CCN)C(C)C.Cl

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