Parecoxib sodium is a non-steroidal anti-inflammatory drug (NSAID) that is used for the treatment of acute pain. It is a prodrug that is rapidly converted to valdecoxib, which is a selective cyclooxygenase-2 (COX-2) inhibitor. Parecoxib sodium is administered intravenously and is commonly used in postoperative pain management.
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Parecoxib is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of COX-2 inhibitors. It is used for the treatment of acute pain and inflammation associated with surgical procedures. Parecoxib is a prodrug that is rapidly converted to valdecoxib, which is the active form of the drug.
Benzenamine, 2,6-diethyl-N-2-imidazolidinylidene-, monohydrochloride, also known as imazalil, is a fungicide that is commonly used in agriculture and horticulture to protect crops from fungal infections. It is also used in the food industry to prevent the growth of mold on fruits and vegetables during storage and transportation. Imazalil is a white crystalline powder that is soluble in water and organic solvents.
L-368,899 hydrochloride is a synthetic compound that belongs to the class of non-peptide oxytocin receptor antagonists. It has been extensively studied for its potential therapeutic applications in various medical conditions, including autism, anxiety, and schizophrenia.
CL 82198 hydrochloride is a synthetic compound that belongs to the class of benzodiazepines. It is a potent and selective agonist of the GABA-A receptor, which is responsible for the regulation of inhibitory neurotransmission in the central nervous system. CL 82198 hydrochloride has been extensively studied for its potential therapeutic applications in various medical conditions, including anxiety, insomnia, and epilepsy.
EGFR (epidermal growth factor receptor), ErbB-2, and ErbB-4 are members of the ErbB family of receptor tyrosine kinases. These receptors play a crucial role in cell growth, differentiation, and survival. Overexpression or mutation of these receptors has been linked to the development and progression of various cancers. Therefore, inhibitors of these receptors have been developed as potential anticancer agents.
High affinity σ1 receptor ligand that displays selectivity over σ2 receptors (Ki values are 10 and 370 nM respectively). Exhibits low affinity for dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters (Ki > 10 μM) and low affinity for dopamine D2 receptors (Ki = 1226 nM). Attenuates cocaine-induced locomotor activity in mice.
O-2545 hydrochloride is a synthetic compound that has gained attention in recent years due to its potential therapeutic and industrial applications. It is a member of the phenylpiperazine class of compounds and has been shown to have a range of biological activities.
Selective estrogen receptor modulator (SERM) that displays selectivity for ERα over ERβ (Ki values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.