BRACO 19 trihydrochloride Inhibitors Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice. 703.1 g/mol
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Formulation: 703.1 g/mol
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BRACO 19 trihydrochloride - 1177798-88-7

BRACO 19 trihydrochloride

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-254581

CAS Number: 1177798-88-7

Molecular Formula: C35H46Cl3N7O2

Molecular Weight: 703.1 g/mol

CAS Number 1177798-88-7
Product Name BRACO 19 trihydrochloride
Molecular Formula C35H46Cl3N7O2
Molecular Weight 703.1 g/mol
InChI InChI=1S/C35H43N7O2.3ClH/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42;;;/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39);3*1H
InChI Key MJAPNWJRLLDPAB-UHFFFAOYSA-N
IUPAC Name N-[9-[4-(dimethylamino)anilino]-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamide;trihydrochloride
Canonical SMILES CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl
Description Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice.
SMILES CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl
Synonyms N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride
PubChem Compound BRACO 19 trihydrochloride
Last Modified Mar 07 2022