BRACO 19 trihydrochloride
Inhibitors
Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice.
703.1 g/mol
Formulation:
703.1 g/mol
Source:
Usage:
BRACO 19 trihydrochloride
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-254581
CAS Number: 1177798-88-7
Molecular Formula: C35H46Cl3N7O2
Molecular Weight: 703.1 g/mol
| CAS Number | 1177798-88-7 |
|---|---|
| Product Name | BRACO 19 trihydrochloride |
| Molecular Formula | C35H46Cl3N7O2 |
| Molecular Weight | 703.1 g/mol |
| InChI | InChI=1S/C35H43N7O2.3ClH/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42;;;/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39);3*1H |
| InChI Key | MJAPNWJRLLDPAB-UHFFFAOYSA-N |
| IUPAC Name | N-[9-[4-(dimethylamino)anilino]-6-(3-pyrrolidin-1-ylpropanoylamino)acridin-3-yl]-3-pyrrolidin-1-ylpropanamide;trihydrochloride |
| Canonical SMILES | CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl |
| Description | Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice. |
| SMILES | CN(C)C1=CC=C(C=C1)NC2=C3C=CC(=CC3=NC4=C2C=CC(=C4)NC(=O)CCN5CCCC5)NC(=O)CCN6CCCC6.Cl.Cl.Cl |
| Synonyms | N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride |
| PubChem Compound | BRACO 19 trihydrochloride |
| Last Modified | Mar 07 2022 |