1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine - 435342-20-4

1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine

Catalog Number: EVT-288430
CAS Number: 435342-20-4
Molecular Formula: C14H20N4
Molecular Weight: 244.34 g/mol
The product is for non-human research only. Not for therapeutic or veterinary use.

Product Introduction

Description
1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine is a chemical compound that has gained significant attention in the scientific community due to its potential therapeutic and industrial applications. This paper aims to provide an overview of the synthesis, chemical structure, biological activity, and potential applications of this compound.
Applications in Various Fields
In medical research, 1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine has been studied for its potential role in drug development. It has been shown to exhibit promising activity against several types of cancer, including breast, lung, and prostate cancer. Clinical trials are currently underway to evaluate its safety and efficacy in humans. In environmental research, this compound has been studied for its effects on ecosystems and its potential role in pollution management. In industrial research, it has been used in manufacturing processes to improve product quality and efficiency. Health and safety considerations should be taken into account during the use of this compound in industrial settings.

Properties

CAS Number

435342-20-4

Product Name

1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine

IUPAC Name

1-(2-piperidin-1-ylethyl)benzimidazol-2-amine

Molecular Formula

C14H20N4

Molecular Weight

244.34 g/mol

InChI

InChI=1S/C14H20N4/c15-14-16-12-6-2-3-7-13(12)18(14)11-10-17-8-4-1-5-9-17/h2-3,6-7H,1,4-5,8-11H2,(H2,15,16)

InChI Key

VIGFYGMAAFDKCA-UHFFFAOYSA-N

SMILES

C1CCN(CC1)CCN2C3=CC=CC=C3N=C2N

Canonical SMILES

C1CCN(CC1)CCN2C3=CC=CC=C3N=C2N
Method of Synthesis or Extraction
Several methods have been reported for the synthesis of 1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine. One of the commonly used methods involves the reaction of 1,2-phenylenediamine with 1-(2-bromoethyl)piperidine in the presence of a palladium catalyst. Another method involves the reaction of 1-(2-aminopropyl)piperidine with 2-bromo-1H-benzimidazole. The efficiency and yield of each method vary depending on the reaction conditions and the purity of the starting materials. Environmental and safety considerations should also be taken into account during the synthesis process to minimize the risk of exposure to hazardous chemicals.
Chemical Structure and Biological Activity
The chemical structure of 1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine consists of a benzimidazole ring and a piperidine moiety. This compound has been reported to exhibit potent inhibitory activity against several enzymes, including protein kinase C and cyclin-dependent kinase 2. It also shows promising activity against cancer cells, with studies reporting its ability to induce apoptosis and inhibit cell proliferation.
Biological Effects
The biological effects of 1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine on cell function and signal transduction have been extensively studied. It has been shown to modulate several signaling pathways, including the MAPK/ERK and PI3K/Akt pathways, which are involved in cell growth and survival. The potential therapeutic and toxic effects of this compound are still being investigated, and further studies are needed to determine its safety and efficacy in humans.
Future Perspectives and Challenges
Despite the promising potential of 1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-amine, there are still several challenges that need to be addressed. One of the main limitations is the lack of understanding of its mechanism of action and its potential side effects. Further studies are needed to determine its safety and efficacy in humans. Possible solutions and improvements include the development of more efficient and environmentally friendly synthesis methods and the identification of new biological targets for this compound. Future trends and prospects in the application of this compound in scientific research are promising, and it is expected to play an important role in the development of new drugs and industrial processes.

Product FAQ

Q1: How Can I Obtain a Quote for a Product I'm Interested In?
  • To receive a quotation, send us an inquiry about the desired product.
  • The quote will cover pack size options, pricing, and availability details.
  • If applicable, estimated lead times for custom synthesis or sourcing will be provided.
  • Quotations are valid for 30 days, unless specified otherwise.
Q2: What Are the Payment Terms for Ordering Products?
  • New customers generally require full prepayment.
  • NET 30 payment terms can be arranged for customers with established credit.
  • Contact our customer service to set up a credit account for NET 30 terms.
  • We accept purchase orders (POs) from universities, research institutions, and government agencies.
Q3: Which Payment Methods Are Accepted?
  • Preferred methods include bank transfers (ACH/wire) and credit cards.
  • Request a proforma invoice for bank transfer details.
  • For credit card payments, ask sales representatives for a secure payment link.
  • Checks aren't accepted as prepayment, but they can be used for post-payment on NET 30 orders.
Q4: How Do I Place and Confirm an Order?
  • Orders are confirmed upon receiving official order requests.
  • Provide full prepayment or submit purchase orders for credit account customers.
  • Send purchase orders to sales@EVITACHEM.com.
  • A confirmation email with estimated shipping date follows processing.
Q5: What's the Shipping and Delivery Process Like?
  • Our standard shipping partner is FedEx (Standard Overnight, 2Day, FedEx International Priority), unless otherwise agreed.
  • You can use your FedEx account; specify this on the purchase order or inform customer service.
  • Customers are responsible for customs duties and taxes on international shipments.
Q6: How Can I Get Assistance During the Ordering Process?
  • Reach out to our customer service representatives at sales@EVITACHEM.com.
  • For ongoing order updates or questions, continue using the same email.
  • Remember, we're here to help! Feel free to contact us for any queries or further assistance.

Quick Inquiry

 Note: Kindly utilize formal channels such as professional, corporate, academic emails, etc., for inquiries. The use of personal email for inquiries is not advised.