Recombinant Human IGFBP1 Protein (His Tag) Recombinant Proteins Recombinant Human Insulin-like Growth Factor-binding Protein 1 is produced in Mammalian cell and the target gene encoding Ala26-Asn259 is fused with a His tag at the C-terminus
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Formulation:
Source: Human Cells
Usage: Our products are for RESEARCH USE ONLY!

Recombinant Human IGFBP1 Protein (His Tag)

Formulation: Human IGFBP1 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Source: Human Cells

Product Name Recombinant Human IGFBP1 Protein (His Tag)
Product Type Recombinant Protein
Source Human Cells
Formulation Human IGFBP1 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Synonym Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, Placental protein 12, PP12
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Description Recombinant Human Insulin-like Growth Factor-binding Protein 1 is produced in Mammalian cell and the target gene encoding Ala26-Asn259 is fused with a His tag at the C-terminus
Host Species Homo sapiens (Human)
Usage Our products are for RESEARCH USE ONLY!
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks..Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
AA Sequence Ala26-Asn259
Product Background Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017]
Uniprot Number P08833