Recombinant Human FGF10 Protein Recombinant Proteins The mature form of human FGF10 (NP_004456.1) (Gln 38-Ser 208) was expressed The recombinant human FGF10 consists of 172a.a and has a predicted molecular weight of 19.6 kDa as estimated in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human FGF10 consists of 172a.a and has a predicted molecular weight of 19.6 kDa as estimated in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Human FGF10 Protein

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-200013

Molecular Weight: The recombinant human FGF10 consists of 172a.a and has a predicted molecular weight of 19.6 kDa as estimated in SDS-PAGE under reducing conditions.

Formulation: Recombinant FGF10 Protein was lyophilized from sterile 20mM Tris, pH 7.51

Source: E. coli

Product Name Recombinant Human FGF10 Protein
Molecular Weight The recombinant human FGF10 consists of 172a.a and has a predicted molecular weight of 19.6 kDa as estimated in SDS-PAGE under reducing conditions.
AA Sequence Gln 38-Ser 208
Bioactivity Measured by its binding ability in a functional ELISA.Immobilized humen FGF10 at 10 ug/ml (100 ul/well) can bind Cynomolgus FGFR1-Fc with a linear range of 31.25-2000 ng/mL.
Formulation Recombinant FGF10 Protein was lyophilized from sterile 20mM Tris, pH 7.51
Host Species Homo sapiens (Human)
Description The mature form of human FGF10 (NP_004456.1) (Gln 38-Ser 208) was expressed
Product Background Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene.Fibroblast growth factor 10 is a paracrine signaling molecule seen first in the limb bud and organogenesis development. FGF10 starts the developing of limbs and its involved in the branching of morphogenesis in multiple organs such as the lungs, skin, ear and salivary glands. During the limb development Tbx4/Tbx5 stimulate the production of FGF10 in the lateral plate mesoderm where it will create an epithelial-mesenchymal FGF signal with FGF8. This positive feedback loop will increase the amount of mesenchyme resulting in a bulge. Afterwards, FGF10 will induce the formation of apical ectodermal ridge (AER) where the foot and hands will be formed. Lung development uses the same epithelial-mesenchymal signaling from FGF10 in the foregut mesenchyme with FGFR2 in the foregut epithelium. FGF10 signaling is required for epithelial branching. Therefore, all branching morphogen organs such as the lungs, skin, ear and salivary glands required the constant expression of FGF10.
Product Memo KGF2 Protein, Human; FGF10, Human
Product Type Recombinant Protein
Purity Greater than 98% as determined by SDS-PAGE
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Synonym FGF10, fibroblast growth factor 10
Terminal Met
Uniprot No O15520
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Aug 20 2021