Recombinant WTAP Protein, Human (GST Tag) Recombinant Proteins The human WTAP isoform 2 (Q15007-2) (Met 1-Arg 151) was fused with the GST tag at the N-terminus The recombinant human WTAP/GST chimera consists of 386a.a and migrates as an approxiamtely 45 kDa band as predicted in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human WTAP/GST chimera consists of 386a.a and migrates as an approxiamtely 45 kDa band as predicted in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant WTAP Protein, Human (GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200070

Molecular Weight: The recombinant human WTAP/GST chimera consists of 386a.a and migrates as an approxiamtely 45 kDa band as predicted in SDS-PAGE under reducing conditions.

Formulation: Recombinant WTAP Protein was lyophilized from sterile 20mM Tris, 0.15M NaCl, 0.5mM GSH, pH 8.01

Source: E. coli

Product Name Recombinant WTAP Protein, Human (GST Tag)
Molecular Weight The recombinant human WTAP/GST chimera consists of 386a.a and migrates as an approxiamtely 45 kDa band as predicted in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Arg 151
Bioactivity Please contact us for detailed information
Formulation Recombinant WTAP Protein was lyophilized from sterile 20mM Tris, 0.15M NaCl, 0.5mM GSH, pH 8.01
Host Species Homo sapiens (Human)
Description The human WTAP isoform 2 (Q15007-2) (Met 1-Arg 151) was fused with the GST tag at the N-terminus
Product Background Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identified as a tumor suppressor for Wilms' tumor, but it is also overexpressed in a variety of cancer cells. The WTAP-WT1 axis in vascular cells suggest that WTAP is a vital and multifaceted regulator of vascular remodeling. WTAP has been suggested to function in alternative splicing, stabilization of mRNA, and cell growth. Knocking down endogenous WTAP increased Smooth muscle cells (SMCs) proliferation, because of increased DNA synthesis and G(1)/S phase transition, together with reduced apoptosis. These effects could be the result of WTAP suppressing the transcriptional activity of WT1 in SMCs. WTAP may thus also play a role in messenger RNA processing in mammalian cells, either dependent on or independent of its interaction with WT1.
Product Memo Mum2 Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Uniprot No Q15007
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019