Recombinant XPNPEP2 Protein, Human (His Tag) Recombinant Proteins The human XPNPEP2 (O43895) (Met 1-Ala 650) without the pro peptide was expressed, with a polyhistidine tag at the C-terminus The recombinant human XPNPEP2 consists of 640a.a and predictes a molecular weight of 72 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh XPNPEP2 is approximately 80 kDa due to glycosylation.
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Formulation: The recombinant human XPNPEP2 consists of 640a.a and predictes a molecular weight of 72 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh XPNPEP2 is approximately 80 kDa due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant XPNPEP2 Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200078

Molecular Weight: The recombinant human XPNPEP2 consists of 640a.a and predictes a molecular weight of 72 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh XPNPEP2 is approximately 80 kDa due to glycosylation.

Formulation: Recombinant XPNPEP2 Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant XPNPEP2 Protein, Human (His Tag)
Molecular Weight The recombinant human XPNPEP2 consists of 640a.a and predictes a molecular weight of 72 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh XPNPEP2 is approximately 80 kDa due to glycosylation.
AA Sequence Met 1-Ala 650
Bioactivity Measured by its ability to cleave the fluorogenic peptide substrate, H-Lys(2-Aminobenzoyl)Pro-Pro-pNitroanilide(K(Abz)PP-pNA).The specific activity is > 300 pmoles/min/ug.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant XPNPEP2 Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Description The human XPNPEP2 (O43895) (Met 1-Ala 650) without the pro peptide was expressed, with a polyhistidine tag at the C-terminus
Product Background Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution to endothelia and brush border epithelia. APP and XPNPEP2 contain homologous blocks of sequence common to members of the "pita bread-fold" protein family, of which Escherichia coli methionine aminopeptidase is the prototype. The C-2399A variant in XPNPEP2 is associated with reduced APP activity and a higher incidence of AE-ACEi. XPNPEP2 mRNA was detected in fibroblasts that carry the translocation, suggesting that this gene at least partially escapes X inactivation. XPNPEP2 is a candidate gene for premature ovarian failure (POF).
Product Memo AEACEI Protein, Human;APP2 Protein, Human
Product Type Recombinant Protein
Purity Greater than 97% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal His 22
Uniprot No O43895
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019