Recombinant Vitronectin Protein, Human (His Tag) Recombinant Proteins The human VTN (NP_000629.3) (Met1-Leu478) was expressed with a polyhistidine tag at the C-terminus The recombinant human VTN consists 470a.a and predicts a molecular weight of 53.7 kDa.
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Formulation: The recombinant human VTN consists 470a.a and predicts a molecular weight of 53.7 kDa.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Vitronectin Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200084

Molecular Weight: The recombinant human VTN consists 470a.a and predicts a molecular weight of 53.7 kDa.

Formulation: Recombinant Vitronectin Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant Vitronectin Protein, Human (His Tag)
Molecular Weight The recombinant human VTN consists 470a.a and predicts a molecular weight of 53.7 kDa.
AA Sequence Met1-Leu478
Bioactivity Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells.When cells are added to Vitronectin-coated plates (10 ug/mL and 100 uL/well), approximately >40% cells will adhere specifically after 30 minutes at 37℃.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method
Formulation Recombinant Vitronectin Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Homo sapiens (Human)
Description The human VTN (NP_000629.3) (Met1-Leu478) was expressed with a polyhistidine tag at the C-terminus
Product Background Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.
Product Memo V75 Protein, Human;Vitronectin Protein, Human;VN Protein, Human;VNT Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE.
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Asp 20
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019