Recombinant TNF-alpha Protein, Cynomolgus Recombinant Proteins The cynomolgus TNF [(Identical to the rhesus TNF (NP_001040614.1)] (Val77-Leu233) was expressed and purified with an initial Met The recombinant cynomolgus TNF consists of 158a.a and has a calculated molecular weight of 17.4 kDa.
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Formulation: The recombinant cynomolgus TNF consists of 158a.a and has a calculated molecular weight of 17.4 kDa.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant TNF-alpha Protein, Cynomolgus

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200359

Molecular Weight: The recombinant cynomolgus TNF consists of 158a.a and has a calculated molecular weight of 17.4 kDa.

Formulation: Recombinant TNF-alpha Protein was lyophilized from sterile 50 mM Tris, 50 mM NaCl, pH 8.0.1

Source: E. coli

Product Name Recombinant TNF-alpha Protein, Cynomolgus
Molecular Weight The recombinant cynomolgus TNF consists of 158a.a and has a calculated molecular weight of 17.4 kDa.
AA Sequence Val77-Leu233
Bioactivity Measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 50-300 pg/ml.
Formulation Recombinant TNF-alpha Protein was lyophilized from sterile 50 mM Tris, 50 mM NaCl, pH 8.0.1
Host Species Cynomolgus
Description The cynomolgus TNF [(Identical to the rhesus TNF (NP_001040614.1)] (Val77-Leu233) was expressed and purified with an initial Met
Product Background Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD12a; p55/6) and TNF-R2 (TNF receptor type 2; CD12b; p75/8), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment. TNF-alpha Protein & AntibodyImmune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019