Recombinant TIMP-1 Protein, Human (Fc Tag) Recombinant Proteins The human TIMP1 (NP_003245.1) (Cys24-Ala207) was expressed with the Fc region of human IgG1 at the N-terminus The recombinant human TIMP1 consists 442a.a and predicts a molecular weight of 49.1 kDa.
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Formulation: The recombinant human TIMP1 consists 442a.a and predicts a molecular weight of 49.1 kDa.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant TIMP-1 Protein, Human (Fc Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-200382

Molecular Weight: The recombinant human TIMP1 consists 442a.a and predicts a molecular weight of 49.1 kDa.

Formulation: Recombinant TIMP-1 Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant TIMP-1 Protein, Human (Fc Tag)
Molecular Weight The recombinant human TIMP1 consists 442a.a and predicts a molecular weight of 49.1 kDa.
AA Sequence Cys24-Ala207
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg protein as determined by the LAL method
Formulation Recombinant TIMP-1 Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Homo sapiens (Human)
Description The human TIMP1 (NP_003245.1) (Cys24-Ala207) was expressed with the Fc region of human IgG1 at the N-terminus
Product Background TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-11, MMP-12, MMP-13 and MMP-16.
Product Memo CLGI Protein, Human;EPA Protein, Human;EPO Protein, Human;HCI Protein, Human;TIMP Protein, Human;TIMP-1 Protein, Human
Product Type Recombinant Protein
Purity Greater than 85% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Glu
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Aug 20 2021