Recombinant Tissue Factor Protein, Rat (His Tag) Recombinant Proteins The rat F3 (Q66HI4) (Met1-Glu252) was expressed, fused with a polyhistidine tag at the C-terminus The recombinant rat F3 comprises 235a.a and predicts a molecular weight of 27.2 kDa. The apparent molecular weight of the recombinant protein is approximately 47-52 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The recombinant rat F3 comprises 235a.a and predicts a molecular weight of 27.2 kDa. The apparent molecular weight of the recombinant protein is approximately 47-52 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Tissue Factor Protein, Rat (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-200395

Molecular Weight: The recombinant rat F3 comprises 235a.a and predicts a molecular weight of 27.2 kDa. The apparent molecular weight of the recombinant protein is approximately 47-52 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation: Recombinant Tissue Factor Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant Tissue Factor Protein, Rat (His Tag)
Molecular Weight The recombinant rat F3 comprises 235a.a and predicts a molecular weight of 27.2 kDa. The apparent molecular weight of the recombinant protein is approximately 47-52 kDa in SDS-PAGE under reducing conditions due to glycosylation.
AA Sequence Met1-Glu252
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Tissue Factor Protein was lyophilized from sterile PBS, pH 7.41
Host Species Rat
Description The rat F3 (Q66HI4) (Met1-Glu252) was expressed, fused with a polyhistidine tag at the C-terminus
Product Background Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating, the plasma serine protease, factor VIIa, following vascular injury. Tissue factor is not only the main physiological initiator of normal blood coagulation, but is also important in the natural history of solid malignancies in that it potentiates metastasis and angiogenesis and mediates outside-in signalling. Tissue factor is expressed constitutively by many tissues which are not in contact with blood and by other cells upon injury or activation; the latter include endothelial cells, tissue macrophages, and peripheral blood monocytes. Coagulation Factor III is a transmembrane glycoprotein that localizes the coagulation serine protease factor VII/VIIa (FVII/VIIa) to the cell surface. The primary function of TF is to activate the clotting cascade. The TF:FVIIa complex also activates cells by cleavage of a G-protein coupled receptor called protease-activated receptor 2 (PAR2). TF is expressed by tumor cells and contributes to a variety of pathologic processes, such as thrombosis, metastasis, tumor growth, and tumor angiogenesis. As a key regulator of haemostasis and angiogenesis, it is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions.
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Ala 29
Uniprot No Q66HI4
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Aug 20 2021