Recombinant Tartrate Resistant Acid Phosphatase Protein, Mouse (His Tag) Recombinant Proteins The pro form of mouse ACP5 (NP_031414.1) (Met 1-Pro 327) was fused with a polyhistidine tag at the C-terminus The recombinant mouse ACP5 consists of 316a.a and has a predicted molecular weight of 35.8 kDa as estimated in SDS-PAGE under reducing conditions.
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Formulation: The recombinant mouse ACP5 consists of 316a.a and has a predicted molecular weight of 35.8 kDa as estimated in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Tartrate Resistant Acid Phosphatase Protein, Mouse (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200513

Molecular Weight: The recombinant mouse ACP5 consists of 316a.a and has a predicted molecular weight of 35.8 kDa as estimated in SDS-PAGE under reducing conditions.

Formulation: Recombinant Tartrate Resistant Acid Phosphatase Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant Tartrate Resistant Acid Phosphatase Protein, Mouse (His Tag)
Molecular Weight The recombinant mouse ACP5 consists of 316a.a and has a predicted molecular weight of 35.8 kDa as estimated in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Pro 327
Bioactivity Measured by its ability to cleave a substrate, p-Nitrophenyl phosphate (pNPP). The specific activity is >9,000 pmoles/min/ug.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Tartrate Resistant Acid Phosphatase Protein was lyophilized from sterile PBS, pH 7.41
Host Species Mouse
Description The pro form of mouse ACP5 (NP_031414.1) (Met 1-Pro 327) was fused with a polyhistidine tag at the C-terminus
Product Background Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone resorption sites, and, once there, TRACP is believed to initiate osteoblast differentiation, activation, and proliferation. TRACP once considered to be just a histochemical marker of osteoclasts is now recognised to be a molecule of widespread occurrence with functions in both the skeleton and the immune system. Two forms of TRACP circulate in human blood, TRACP 5a derived from macrophages and dendritic cells, and TRACP-5b derived from osteoclasts. Recent data have demonstrated the utility of TRACP-5b as a marker of osteoclast number and bone resorption, and serum TRACP-5a as a marker of inflammatory conditions. TRACP is expressed by osteoclasts, macrophages, dendritic cells and a number of other cell types. It has a critical role in many biological processes including skeletal development, collagen synthesis and degradation, the mineralisation of bone, cytokine production by macrophages and dendritic cells, macrophage recruitment, dendritic cell maturation and a role in the development of Th1 responses.
Product Memo TRACP Protein, Mouse;TRAP Protein, Mouse
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Ala 23
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019