Recombinant TBG Protein, Human (His Tag) Recombinant Proteins The human SERPINA7 (NP_000345.2) (Met 1-Ala 415) was expressed, fused with a polyhistidine tag at the C-terminus The secreted recombinant human SERPINA7 comprises 406a.a and has a predicted molecular weight of 45.5 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
$ $99 In stock
Formulation: The secreted recombinant human SERPINA7 comprises 406a.a and has a predicted molecular weight of 45.5 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant TBG Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200514

Molecular Weight: The secreted recombinant human SERPINA7 comprises 406a.a and has a predicted molecular weight of 45.5 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant TBG Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant TBG Protein, Human (His Tag)
Molecular Weight The secreted recombinant human SERPINA7 comprises 406a.a and has a predicted molecular weight of 45.5 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Ala 415
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant TBG Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Description The human SERPINA7 (NP_000345.2) (Met 1-Ala 415) was expressed, fused with a polyhistidine tag at the C-terminus
Product Background Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to theserpin family. TBG is synthesized primarily in theliveras a 54 kDa protein.TBG is genomically aserpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins(along with transthyretin and albumin) responsible for carrying thethyroidhormones thyroxine(T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 inserum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with itsligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.
Product Memo TBG Protein, Human
Product Type Recombinant Protein
Purity Greater than 97% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Ala 21
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019