Recombinant TCN2 Protein, Human (His Tag) Recombinant Proteins The human TCN2 (NP_000346.2) (Met 1-Trp 427) was expressed with a C-terminal polyhistidine tag The secreted recombinant human TCN2 comprises 418a.a with a predicted molecular weight of 46.7 kDa. It migrates with the molecular weight of approximately 44 kDa in SDS-PAGE under reducing conditions.
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Formulation: The secreted recombinant human TCN2 comprises 418a.a with a predicted molecular weight of 46.7 kDa. It migrates with the molecular weight of approximately 44 kDa in SDS-PAGE under reducing conditions.
Source: CHO Stable Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant TCN2 Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200518

Molecular Weight: The secreted recombinant human TCN2 comprises 418a.a with a predicted molecular weight of 46.7 kDa. It migrates with the molecular weight of approximately 44 kDa in SDS-PAGE under reducing conditions.

Formulation: Recombinant TCN2 Protein was lyophilized from sterile PBS, pH 7.4.1

Source: CHO Stable Cells

Product Name Recombinant TCN2 Protein, Human (His Tag)
Molecular Weight The secreted recombinant human TCN2 comprises 418a.a with a predicted molecular weight of 46.7 kDa. It migrates with the molecular weight of approximately 44 kDa in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Trp 427
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant TCN2 Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Homo sapiens (Human)
Description The human TCN2 (NP_000346.2) (Met 1-Trp 427) was expressed with a C-terminal polyhistidine tag
Product Background Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 2 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.
Product Memo D22S676 Protein, Human;D22S750 Protein, Human;II Protein, Human;TC Protein, Human;TC-2 Protein, Human;TC2 Protein, Human;TCII Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source CHO Stable Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Glu 19
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019