Recombinant STK40 Protein, Human (His & GST Tag) Recombinant Proteins The human STK40 (NP_114406) (Met1-Lys435) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant human STK40 /GST chimera consists of 672a.a and has a calculated molecular weight of 76.8 kDa. The recombinant protein migrates as an approximately 85 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human STK40 /GST chimera consists of 672a.a and has a calculated molecular weight of 76.8 kDa. The recombinant protein migrates as an approximately 85 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant STK40 Protein, Human (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200545

Molecular Weight: The recombinant human STK40 /GST chimera consists of 672a.a and has a calculated molecular weight of 76.8 kDa. The recombinant protein migrates as an approximately 85 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant STK40 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, 3mM DTT, 0.5M Urea, 0.5mM GSH, pH 8.01

Source: Baculovirus-Insect Cells

Product Name Recombinant STK40 Protein, Human (His & GST Tag)
Molecular Weight The recombinant human STK40 /GST chimera consists of 672a.a and has a calculated molecular weight of 76.8 kDa. The recombinant protein migrates as an approximately 85 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met1-Lys435
Bioactivity Kinase activity untested
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant STK40 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, 3mM DTT, 0.5M Urea, 0.5mM GSH, pH 8.01
Host Species Homo sapiens (Human)
Description The human STK40 (NP_114406) (Met1-Lys435) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background STK4 localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk4 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk4 is able to activate the Erk/MAPK pathway and induce extraembryonic-endoderm (ExEn) differentiation in mouse ESCs. Interestingly, cells overexpressing Stk4 exclusively contribute to the ExEn layer of chimeric embryos when injected into host blastocysts. In contrast, deletion of Stk4 in ESCs markedly reduces ExEn differentiation in vitro. STK4 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK4 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK4 that are produced as a result of alternative splicing.
Product Memo SgK495 Protein, Human;SHIK Protein, Human
Product Type Recombinant Protein
Purity Greater than 97% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use