Recombinant Sphingosine Kinase 1 Protein, Human Recombinant Proteins The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
$ $99 In stock
Formulation: The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Sphingosine Kinase 1 Protein, Human

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200583

Molecular Weight: The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.1

Source: Baculovirus-Insect Cells

Product Name Recombinant Sphingosine Kinase 1 Protein, Human
Molecular Weight The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met1-Leu384
Bioactivity The specific activity was determined to be 1028 nmol/min/mg using Sphingosine Kinase Substrate as substrate.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.1
Host Species Homo sapiens (Human)
Description The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus
Product Background SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
Product Memo SPHK Protein, Human;SPHK1 Protein, Human;SPK Protein, Human
Product Type Recombinant Protein
Purity Greater than 85% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Gly
Uniprot No Q9NYA1
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019