Recombinant Sphingosine Kinase 1 Protein, Human
Others
The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus
The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
Formulation:
The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
Source:
Baculovirus-Insect Cells
Usage:
Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Recombinant Sphingosine Kinase 1 Protein, Human
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-200583
Molecular Weight: The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions.
Formulation: Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.1
Source: Baculovirus-Insect Cells
| Product Name | Recombinant Sphingosine Kinase 1 Protein, Human |
|---|---|
| Molecular Weight | The recombinant human SPHK1 consists of 386a.a and has a calculated molecular weight of 42.7 kDa. The recombinant protein migrates as an approximately 46 kDa band in SDS-PAGE under reducing conditions. |
| AA Sequence | Met1-Leu384 |
| Bioactivity | The specific activity was determined to be 1028 nmol/min/mg using Sphingosine Kinase Substrate as substrate. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Formulation | Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.1 |
| Host Species | Homo sapiens (Human) |
| Description | The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus |
| Product Background | SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. |
| Product Memo | SPHK Protein, Human;SPHK1 Protein, Human;SPK Protein, Human |
| Product Type | Recombinant Protein |
| Source | Baculovirus-Insect Cells |
| Storage | Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Terminal | Gly |
| Uniprot No | Q9NYA1 |
| Usage | Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use |
| Last Modified | Jul 26 2021 |