Recombinant Sphingosine Kinase 1 Protein, Human (His & GST Tag) Recombinant Proteins The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus The secreted recombinant human SPHK1 consists of 621a.a and predicts a molecular weight of 70.3 KDa. The apparent molecular weight of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The secreted recombinant human SPHK1 consists of 621a.a and predicts a molecular weight of 70.3 KDa. The apparent molecular weight of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Sphingosine Kinase 1 Protein, Human (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200586

Molecular Weight: The secreted recombinant human SPHK1 consists of 621a.a and predicts a molecular weight of 70.3 KDa. The apparent molecular weight of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation: Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0.1

Source: Baculovirus-Insect Cells

Product Name Recombinant Sphingosine Kinase 1 Protein, Human (His & GST Tag)
Molecular Weight The secreted recombinant human SPHK1 consists of 621a.a and predicts a molecular weight of 70.3 KDa. The apparent molecular weight of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation.
AA Sequence Met1-Leu384
Bioactivity Kinase activity untested
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Sphingosine Kinase 1 ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0.1
Host Species Homo sapiens (Human)
Description The human SPHK1 (Q9NYA1-1)(Met1-Leu384) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
Product Memo SPHK Protein, Human;SPHK1 Protein, Human;SPK Protein, Human
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Uniprot No Q9NYA1
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019