Recombinant Src Protein, Mouse (His & GST Tag) Recombinant Proteins The mouse SRC (NP_001020566.111) (Met 1-Leu 535) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant mouse SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant mouse SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Src Protein, Mouse (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200597

Molecular Weight: The recombinant mouse SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant Src ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.01

Source: Baculovirus-Insect Cells

Product Name Recombinant Src Protein, Mouse (His & GST Tag)
Molecular Weight The recombinant mouse SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Leu 535
Bioactivity 1. The specific activity was determined to be >80 nmol/min/mg using poly [Glu, Tyr] 4 1 as substrate.2. Measured by its binding ability in a functional ELISA. Immobilized recombinant Mouse SRC at 2 ug/ml (100 ul/well) can bind biotinylated human PTPRA (aa 174-793) with a linear range of 0.032-0.8 ug/ml.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Src ProteinSupplied as sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.01
Host Species Mouse
Description The mouse SRC (NP_001020566.111) (Met 1-Leu 535) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.
Product Memo AW259666 Protein, Mouse;pp60c-src Protein, Mouse
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019