Recombinant Src Protein, Human (His & GST Tag) Recombinant Proteins The human SRC (P12931-1) (Met 1-Leu 536) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant human SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 KDa. It migrates as an approximately 81 KDa band in SDS-PAGE under non-reduced conditions.
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Formulation: The recombinant human SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 KDa. It migrates as an approximately 81 KDa band in SDS-PAGE under non-reduced conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Src Protein, Human (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200598

Molecular Weight: The recombinant human SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 KDa. It migrates as an approximately 81 KDa band in SDS-PAGE under non-reduced conditions.

Formulation: Recombinant Src ProteinSupplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0.3mM DTT1

Source: Baculovirus-Insect Cells

Product Name Recombinant Src Protein, Human (His & GST Tag)
Molecular Weight The recombinant human SRC/GST chimera consists of 773a.a and has a calculated molecular weight of 87.7 KDa. It migrates as an approximately 81 KDa band in SDS-PAGE under non-reduced conditions.
AA Sequence Met 1-Leu 536
Bioactivity The specific activity was determined to be >80 nmol/min/mg using Poly(Glu Tyr) 4 1 as substrate.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Src ProteinSupplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0.3mM DTT1
Host Species Homo sapiens (Human)
Description The human SRC (P12931-1) (Met 1-Leu 536) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.
Product Memo ASV Protein, Human;c-SRC Protein, Human;p60-Src Protein, Human;SRC1 Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Uniprot No P12931
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019