Recombinant SGK3 Protein, Human (His & GST Tag) Recombinant Proteins The human SGK3 (Q96BR1-1) (Met 1-Leu 496) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant human SGK3/GST chimera consists of 733a.a and has a calculated molecular weight of 85 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human SGK3/GST chimera consists of 733a.a and has a calculated molecular weight of 85 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant SGK3 Protein, Human (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-200666

Molecular Weight: The recombinant human SGK3/GST chimera consists of 733a.a and has a calculated molecular weight of 85 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant SGK3 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 0.5mM PMSF, 10% gly, 1mM GSH, pH 7.41

Source: Baculovirus-Insect Cells

Product Name Recombinant SGK3 Protein, Human (His & GST Tag)
Molecular Weight The recombinant human SGK3/GST chimera consists of 733a.a and has a calculated molecular weight of 85 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Leu 496
Bioactivity No Kinase Activity
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant SGK3 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 0.5mM PMSF, 10% gly, 1mM GSH, pH 7.41
Host Species Homo sapiens (Human)
Description The human SGK3 (Q96BR1-1) (Met 1-Leu 496) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein which belongs to theprotein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains oneAGC-kinase C-terminal domain, oneprotein kinase domain and one PX (phox homology) domain. Two specific sites of SGK3, one in the kinase domain (Thr-32) and the other in the C-terminal regulatory region (Ser-486), is needed to be phosphorylated for its full activation. SGK3 is expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle. SGK3 is involved in the activation of potassium channels. It mediates cell IL-3-dependent survival signals. SGK3 participates in the regulation of HERG by increasing HERG protein abundance in the plasma membrane and may thus modify the duration of the cardiac action potential. SGK3 is also a very important and characteristic molecule that plays a critical role in both hair follicle morphogenesis and hair cycling.
Product Memo CISK Protein, Human;SGK2 Protein, Human;SGKL Protein, Human
Product Type Recombinant Protein
Purity Greater than 80% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Uniprot No Q96BR1
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Aug 20 2021