Recombinant SerpinB6 Protein, Human (His Tag) Recombinant Proteins The human SERPINB6 (AAB30320.1) (Asp 2-Pro 376) was expressed, with a polyhistidine tag at the N-terminus The recombinant human SERPINB6 consists of 394a.a and predicts a molecular weight of 44.9 kDa. It migrates as an approximately 43 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human SERPINB6 consists of 394a.a and predicts a molecular weight of 44.9 kDa. It migrates as an approximately 43 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant SerpinB6 Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200685

Molecular Weight: The recombinant human SERPINB6 consists of 394a.a and predicts a molecular weight of 44.9 kDa. It migrates as an approximately 43 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant SerpinB6 Protein was lyophilized from sterile PBS, pH 7.41

Source: Baculovirus-Insect Cells

Product Name Recombinant SerpinB6 Protein, Human (His Tag)
AA Sequence Asp 2-Pro 376
Bioactivity Please contact us for detailed information
Description The human SERPINB6 (AAB30320.1) (Asp 2-Pro 376) was expressed, with a polyhistidine tag at the N-terminus
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant SerpinB6 Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Molecular Weight The recombinant human SERPINB6 consists of 394a.a and predicts a molecular weight of 44.9 kDa. It migrates as an approximately 43 kDa band in SDS-PAGE under reducing conditions.
Product Background SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein which belongs to theserpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is expressed in keratinocytes (at protein level). It is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. SerpinB6 / PI-6 is expressed in the inner ear hair cells. It expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. SerpinB6 / PI-6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Defects in SerpinB6 are the cause of deafness autosomal recessive type 91 which is a form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal.
Product Memo CAP Protein, Human;DFNB91 Protein, Human;DKFZp686I04222 Protein, Human;MGC111370 Protein, Human;MSTP057 Protein, Human;PI-6 Protein, Human;PI6 Protein, Human;PTI Protein, Human;RP1-90J20.6 Protein, Human;SPI3 Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use