Recombinant REG4 Protein, Human (His Tag) Recombinant Proteins The human REG4 (NP_001152824.1) (Met 1-Pro 158) was expressed, with a polyhistidine tag at the C-terminus The recombinant human REG4 consists of 147a.a and predictes a molecular weight of 17.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh REG4 is approximately 18 and 22 kDa due to different glycosylation.
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Formulation: The recombinant human REG4 consists of 147a.a and predictes a molecular weight of 17.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh REG4 is approximately 18 and 22 kDa due to different glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant REG4 Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-200860

Molecular Weight: The recombinant human REG4 consists of 147a.a and predictes a molecular weight of 17.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh REG4 is approximately 18 and 22 kDa due to different glycosylation.

Formulation: Recombinant REG4 Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant REG4 Protein, Human (His Tag)
AA Sequence Met 1-Pro 158
Bioactivity Measured by the ability of the immobilized protein to support the proliferation of HCT-116 human colorectal carcinoma cells (ATCC CCL-247) under low serum conditions.The ED50 for this effect is typically 4-20 ug/ml.
Description The human REG4 (NP_001152824.1) (Met 1-Pro 158) was expressed, with a polyhistidine tag at the C-terminus
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant REG4 Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Molecular Weight The recombinant human REG4 consists of 147a.a and predictes a molecular weight of 17.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rh REG4 is approximately 18 and 22 kDa due to different glycosylation.
Product Background Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
Product Memo GISP Protein, Human;REG-IV Protein, Human;RELP Protein, Human
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Ala 26
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use