Recombinant PSME2 Protein, Human (His Tag) Recombinant Proteins The human PSME2 (Met1-Tyr239) was expressed with a polyhistidine tag at the N-terminus The recombinant human PSME2 consists of 254a.a and predicts a molecular weight of 29.2 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions.
$ $99 In stock
Formulation: The recombinant human PSME2 consists of 254a.a and predicts a molecular weight of 29.2 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant PSME2 Protein, Human (His Tag)

Formulation: Recombinant PSME2 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, 1mM DTT, pH 8.0.1

Source: E. coli

Product Name Recombinant PSME2 Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant PSME2 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, 1mM DTT, pH 8.0.1
Molecular Weight The recombinant human PSME2 consists of 254a.a and predicts a molecular weight of 29.2 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions.
Purity Greater than 90% as determined by SDS-PAGE
Description The human PSME2 (Met1-Tyr239) was expressed with a polyhistidine tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Tyr239
Product Background PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME2 gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring.
Memo PA28B Protein, Human;PA28beta Protein, Human;REGbeta Protein, Human
Terminal His
Bioactivity Please contact us for detailed information