Recombinant PSME3 Protein, Human (His Tag) Recombinant Proteins The human PSME3 (P61289-1) (Met1-Tyr254) was expressed with a polyhistidine tag at the N-terminus The recombinant human PSME3 consists of 269a.a and predicts a molecular weight of 31.3 KDa. It migrates as an approximately 28-33 KDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human PSME3 consists of 269a.a and predicts a molecular weight of 31.3 KDa. It migrates as an approximately 28-33 KDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant PSME3 Protein, Human (His Tag)

Formulation: Recombinant PSME3 Protein was lyophilized from sterile 50mM Tris, 200mM NaCl, 40% Glycerol, pH 8.0.1

Source: E. coli

Product Name Recombinant PSME3 Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant PSME3 Protein was lyophilized from sterile 50mM Tris, 200mM NaCl, 40% Glycerol, pH 8.0.1
Molecular Weight The recombinant human PSME3 consists of 269a.a and predicts a molecular weight of 31.3 KDa. It migrates as an approximately 28-33 KDa band in SDS-PAGE under reducing conditions.
Purity Greater than 90% as determined by SDS-PAGE
Description The human PSME3 (P61289-1) (Met1-Tyr254) was expressed with a polyhistidine tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Tyr254
Product Background PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring.
Memo HEL-S-283 Protein, Human;Ki Protein, Human;PA28-gamma Protein, Human;PA28G Protein, Human;PA28gamma Protein, Human;REG-GAMMA Protein, Human
Uniprot Number P61289
Terminal His
Bioactivity Please contact us for detailed information