Recombinant PCBP1 Protein, Human (His Tag)
Others
The human PCBP1 (NP_006187.2) (Asp 2-Cys 356) was expressed, with a polyhistidine tag at the N-terminus
The recombinant human PCBP1 comprises 362a.a and has a predicted molecular weight of 38.3 kDa. It migrates as an approximately 42 kDa band in SDS-PAGE under reducing conditions.
Formulation:
The recombinant human PCBP1 comprises 362a.a and has a predicted molecular weight of 38.3 kDa. It migrates as an approximately 42 kDa band in SDS-PAGE under reducing conditions.
Source:
E. coli
Usage:
Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Recombinant PCBP1 Protein, Human (His Tag)
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-201249
Molecular Weight: The recombinant human PCBP1 comprises 362a.a and has a predicted molecular weight of 38.3 kDa. It migrates as an approximately 42 kDa band in SDS-PAGE under reducing conditions.
Formulation: Recombinant PCBP1 Protein was lyophilized from sterile 50mM Tris, 500mM NaCl, 20% glycerol, pH 8.01
Source: E. coli
| Product Name | Recombinant PCBP1 Protein, Human (His Tag) |
|---|---|
| Molecular Weight | The recombinant human PCBP1 comprises 362a.a and has a predicted molecular weight of 38.3 kDa. It migrates as an approximately 42 kDa band in SDS-PAGE under reducing conditions. |
| AA Sequence | Asp 2-Cys 356 |
| Bioactivity | Please contact us for detailed information |
| Formulation | Recombinant PCBP1 Protein was lyophilized from sterile 50mM Tris, 500mM NaCl, 20% glycerol, pH 8.01 |
| Host Species | Homo sapiens (Human) |
| Description | The human PCBP1 (NP_006187.2) (Asp 2-Cys 356) was expressed, with a polyhistidine tag at the N-terminus |
| Product Background | Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. PCBP1 is widely expressed in many human tissues and involved in regulation of transcription, transportation process, and function of RNA molecules. PCBP1 plays a pivotal role in post-transcriptional regulation for RNA metabolism and RNA function in gene expression. PCBP1 acts as a negative regulator of CD44 variants splicing in HepG2 cells, and loss of PCBP1 in human hepatic tumor contributes to the formation of a metastatic phenotype. |
| Product Memo | HEL-S-85 Protein, Human;hnRNP-E1 Protein, Human;hnRNP-X Protein, Human;HNRPE1 Protein, Human;HNRPX Protein, Human |
| Product Type | Recombinant Protein |
| Source | E. coli |
| Storage | Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Terminal | Met |
| Usage | Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use |
| Last Modified | Jul 26 2021 |