Recombinant OX40 Protein, Rat (Fc Tag)
Others
The rat Tnfrsf4 (NP_037181.1) (Val20-Pro210) was expressed with the Fc region of human IgG1 at the C-terminus
The recombinant rat Tnfrsf4 consists of 429a.a and predicts a molecular weight of 47.8 kDa.
Formulation:
The recombinant rat Tnfrsf4 consists of 429a.a and predicts a molecular weight of 47.8 kDa.
Source:
HEK293 Cells
Usage:
Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Recombinant OX40 Protein, Rat (Fc Tag)
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog Number: BT-201288
Molecular Weight: The recombinant rat Tnfrsf4 consists of 429a.a and predicts a molecular weight of 47.8 kDa.
Formulation: Recombinant OX40 Protein was lyophilized from sterile PBS, pH 7.4.1
Source: HEK293 Cells
Product Name | Recombinant OX40 Protein, Rat (Fc Tag) |
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Molecular Weight | The recombinant rat Tnfrsf4 consists of 429a.a and predicts a molecular weight of 47.8 kDa. |
AA Sequence | Val20-Pro210 |
Bioactivity | Please contact us for detailed information |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method |
Formulation | Recombinant OX40 Protein was lyophilized from sterile PBS, pH 7.4.1 |
Host Species | Rat |
Description | The rat Tnfrsf4 (NP_037181.1) (Val20-Pro210) was expressed with the Fc region of human IgG1 at the C-terminus |
Product Background | OX4 (CD134) and its binding partner, OX4L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX4 and OX4L plays an important role in antigen-specific T-cell expansion and survival. OX4 and OX4L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX4-OX4L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX4 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Immune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsCo-stimulatory Immune Checkpoint Targets ImmunotherapyCancer ImmunotherapyTargeted Therapy |
Product Type | Recombinant Protein |
Source | HEK293 Cells |
Storage | Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Terminal | Val 20 |
Usage | Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use |
Last Modified | Jul 26 2021 |