Recombinant Oncostatin M Protein, Mouse Others The mouse OSM (P53347) (Ala24-Arg206) was expressed with an initial Met at the N-terminal The recombinant mouse OSM consists of 184a.a and predicts a molecular weight of 20.7 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant mouse OSM consists of 184a.a and predicts a molecular weight of 20.7 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Recombinant Oncostatin M Protein, Mouse -

Recombinant Oncostatin M Protein, Mouse

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-201302

Molecular Weight: The recombinant mouse OSM consists of 184a.a and predicts a molecular weight of 20.7 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant Oncostatin M Protein was lyophilized from sterile PBS, pH 7.4.1

Source: E. coli

Product Name Recombinant Oncostatin M Protein, Mouse
Molecular Weight The recombinant mouse OSM consists of 184a.a and predicts a molecular weight of 20.7 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
AA Sequence Ala24-Arg206
Bioactivity 1. Measured by its ability to inhibit proliferation of M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10-50 ng/mL.2. Measured in a cell proliferation assay using NIH3T3 cells. The ED50 for this effect is typically 8-32 ng/mL.
Formulation Recombinant Oncostatin M Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Mouse
Description The mouse OSM (P53347) (Ala24-Arg206) was expressed with an initial Met at the N-terminal
Product Background Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp13 and takes part in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development. Oncostatin M (OSM) was previoustly identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6 and G-CSF, has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. The human form of OSM is insensitive between pH2 and 11 and resistant to heating for one hour at 56 degree but is not stable at 9 degrees. The human OSM is produced as a precursor containing 252 amino acids, whose first 25 amino acids function as a secretory signal peptide and which on removal yields the soluble 227 amino acid pro-OSM. Removal of the C-teminal most 31 amino acids produces the fully active 196 residue form.
Product Memo OncoM Protein, Mouse
Product Type Recombinant Protein
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Uniprot No P53347
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Jul 26 2021