Recombinant MDGA2 Protein, Mouse (His Tag) Recombinant Proteins The mouse MDGA2 isoform 1 (P60755-1) without the propeptide (Met 1-Asp 924) was expressed, fused with a polyhistidine tag at the C-terminus The secreted recombinant mouse MDGA2 comprises 910a.a and has a predicted molecular weight of 103 kDa. As a result of glycosylation, the apparent molecular weight of rm MDGA2 is approximately 110-120 kDa in SDS-PAGE under reducing conditions.
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Formulation: The secreted recombinant mouse MDGA2 comprises 910a.a and has a predicted molecular weight of 103 kDa. As a result of glycosylation, the apparent molecular weight of rm MDGA2 is approximately 110-120 kDa in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant MDGA2 Protein, Mouse (His Tag)

Formulation: Recombinant MDGA2 Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant MDGA2 Protein, Mouse (His Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant MDGA2 Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The secreted recombinant mouse MDGA2 comprises 910a.a and has a predicted molecular weight of 103 kDa. As a result of glycosylation, the apparent molecular weight of rm MDGA2 is approximately 110-120 kDa in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 90% as determined by SDS-PAGE
Description The mouse MDGA2 isoform 1 (P60755-1) without the propeptide (Met 1-Asp 924) was expressed, fused with a polyhistidine tag at the C-terminus
Host Species Mouse
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Asp 924
Product Background MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2 and MAMDC1, is a cell membrane protein which contains sixIg-like (immunoglobulin-like) domains and oneMAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated, and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance.
Memo 6720489L24Rik Protein, Mouse;9330209L04Rik Protein, Mouse;Adp Protein, Mouse;Mamdc1 Protein, Mouse
Uniprot Number P60755
Terminal Pro 26
Bioactivity Please contact us for detailed information