Recombinant MDMX Protein, Human (His Tag) Recombinant Proteins The human MDM4 (NP_002384.2) (Met1-Asp134) was expressed with a polyhistidine tag at the N-terminus The recombinant human MDM4 consists of 152a.a and predicts a molecular weight of 17 KDa. It migrates as an approximately 19.4 KDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human MDM4 consists of 152a.a and predicts a molecular weight of 17 KDa. It migrates as an approximately 19.4 KDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant MDMX Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-201594

Molecular Weight: The recombinant human MDM4 consists of 152a.a and predicts a molecular weight of 17 KDa. It migrates as an approximately 19.4 KDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant MDMX Protein was lyophilized from sterile PBS, pH 7.4.1

Source: E. coli

Product Name Recombinant MDMX Protein, Human (His Tag)
Molecular Weight The recombinant human MDM4 consists of 152a.a and predicts a molecular weight of 17 KDa. It migrates as an approximately 19.4 KDa band in SDS-PAGE under reducing conditions.
AA Sequence Met1-Asp134
Bioactivity Please contact us for detailed information
Formulation Recombinant MDMX Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Homo sapiens (Human)
Description The human MDM4 (NP_002384.2) (Met1-Asp134) was expressed with a polyhistidine tag at the N-terminus
Product Background MDM4 (also called MDMX) is a promising target for cancer therapy, as it is undetectable in most normal adult tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function.MDM4, an essential negative regulator of the P53 tumor suppressor, is frequently overexpressed in cancer cells that harbor a wild-type P53.MDM4 is a key regulator of p53, whose biological activities depend on both transcriptional activity and transcription-independent mitochondrial functions. MDM4 binds to p53 and blocks its transcriptional activity. MDM4 is a negative regulator of p53 and cooperates with MDM2 in the cellular response to DNA damage.
Product Memo HDMX Protein, Human;MDMX Protein, Human;MRP1 Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal His
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019