Recombinant MEK2 Protein, Human (GST Tag) Recombinant Proteins The human MAP2K2 (NP_109587.1) (Met 1-Val 400) was fused with the GST tag at the N-terminus The recombinant human MAP2K2/GST chimera consists of 624a.a and has a calculated molecular weight of 70.7 kDa. It migrates as an approximately 66 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human MAP2K2/GST chimera consists of 624a.a and has a calculated molecular weight of 70.7 kDa. It migrates as an approximately 66 kDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant MEK2 Protein, Human (GST Tag)

Formulation: Recombinant MEK2 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 2mM GSH, pH 7.41

Source: Baculovirus-Insect Cells

Product Name Recombinant MEK2 Protein, Human (GST Tag)
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Formulation Recombinant MEK2 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 2mM GSH, pH 7.41
Molecular Weight The recombinant human MAP2K2/GST chimera consists of 624a.a and has a calculated molecular weight of 70.7 kDa. It migrates as an approximately 66 kDa band in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 92% as determined by SDS-PAGE
Description The human MAP2K2 (NP_109587.1) (Met 1-Val 400) was fused with the GST tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Val 400
Product Background Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains oneprotein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion and growth factor signaling. MAP2K1 / MEK1 is a crucial modulator of Mek and Erk signaling and have potential implications for the role of MEK1 and MEK2 in tumorigenesis. MAP2K2 / MEK2 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. It also activates the ERK1 and ERK2 MAP kinases. Defects in MAP2K2 are a cause of cardiofaciocutaneous syndrome (CFC syndrome) which is characterized by a distinctive facial appearance, heart defects and mental retardation. Heart defects include pulmonic stenosis, atrial septal defects and hypertrophic cardiomyopathy.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy
Memo CFC4 Protein, Human;FLJ26075 Protein, Human;MAPKK2 Protein, Human;MEK2 Protein, Human;MKK2 Protein, Human;PRKMK2 Protein, Human
Terminal Met
Bioactivity No Kinase Activity