Recombinant MCP2 Protein, Human (SUMO Tag) Recombinant Proteins The human CCL8 (P80075-1) (Gln 24-Pro 99) was fused with the SUMO tag at the N-terminus The recombinant human CCL8 consisting of 187a.a and has a calculated molecular weight of 21.7 kDa. The apparent molecular weight of the protein is approximately 30 kDa in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human CCL8 consisting of 187a.a and has a calculated molecular weight of 21.7 kDa. The apparent molecular weight of the protein is approximately 30 kDa in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant MCP2 Protein, Human (SUMO Tag)

Formulation: Recombinant MCP2 Protein was lyophilized from sterile PBS, pH 7.41

Source: E. coli

Product Name Recombinant MCP2 Protein, Human (SUMO Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant MCP2 Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The recombinant human CCL8 consisting of 187a.a and has a calculated molecular weight of 21.7 kDa. The apparent molecular weight of the protein is approximately 30 kDa in SDS-PAGE under reducing conditions.
Purity Greater than 90% as determined by SDS-PAGE
Description The human CCL8 (P80075-1) (Gln 24-Pro 99) was fused with the SUMO tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Gln 24-Pro 99
Product Background Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP-2), is a small cytokine belonging to the C-C chemokine family. CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. CCL8's ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.
Memo HC14 Protein, Human;MCP-2 Protein, Human;MCP2 Protein, Human;SCYA10 Protein, Human;SCYA8 Protein, Human
Uniprot Number P80075
Terminal Met
Bioactivity Please contact us for detailed information