Recombinant LBP Protein, Human (His Tag) Recombinant Proteins The human LBP (NP_004130.2) extracellular domain (Met 1-Val 481) was fused with the a polyhistidine tag at the C-terminus The recombinant human LBP consists of 467a.a and has a predicted molecular weight of 52.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rhLBP is approximately 62 kDa due to glycosylation.
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Formulation: The recombinant human LBP consists of 467a.a and has a predicted molecular weight of 52.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rhLBP is approximately 62 kDa due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant LBP Protein, Human (His Tag)

Formulation: Recombinant LBP Protein was lyophilized from sterile 20mM Tris, 100mM NaCl, 0.05mM EDTA, pH 8.01

Source: HEK293 Cells

Product Name Recombinant LBP Protein, Human (His Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant LBP Protein was lyophilized from sterile 20mM Tris, 100mM NaCl, 0.05mM EDTA, pH 8.01
Molecular Weight The recombinant human LBP consists of 467a.a and has a predicted molecular weight of 52.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular weight of rhLBP is approximately 62 kDa due to glycosylation.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 95% as determined by SDS-PAGE
Description The human LBP (NP_004130.2) extracellular domain (Met 1-Val 481) was fused with the a polyhistidine tag at the C-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Val 481
Product Background Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and to purified aggregates of extracted endotoxin, and catalyses the delivery of endotoxin to membrane ( mCD14,GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to endotoxin. LBP efficiently catalyses the transfer of individual molecules of endotoxin to (s)CD14 only when LBP–endotoxin aggregates are formed in the presence of albumin. In the presence of EDTA, LBP binding promotes further disaggregation of endotoxin. LBP binding does not have such drastic effects under more physiological conditions, but may still induce more subtle topological rearrangements of endotoxin.
Memo BPIFD2 Protein, Human
Terminal Ala 26
Bioactivity Please contact us for detailed information