Recombinant LAG3 Protein, Rat (His Tag) Recombinant Proteins The rat LAG3 (Q5BK54)(Met1-Leu442) was expressed with a polyhistidine tag at the C-terminus The recombinant rat LAG3 comprises 430a.a and predicts a molecular weight of 47.1 kDa. The apparent molecular weight of the recombinant protein is approximately 55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The recombinant rat LAG3 comprises 430a.a and predicts a molecular weight of 47.1 kDa. The apparent molecular weight of the recombinant protein is approximately 55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant LAG3 Protein, Rat (His Tag)

Formulation: Recombinant LAG3 Protein was lyophilized from sterile 20 mM NaAc, 500 mM NaCl, 10 % Glycerol, 0.02 % tween 20, pH 5.5.1

Source: HEK293 Cells

Product Name Recombinant LAG3 Protein, Rat (His Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant LAG3 Protein was lyophilized from sterile 20 mM NaAc, 500 mM NaCl, 10 % Glycerol, 0.02 % tween 20, pH 5.5.1
Molecular Weight The recombinant rat LAG3 comprises 430a.a and predicts a molecular weight of 47.1 kDa. The apparent molecular weight of the recombinant protein is approximately 55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 90% as determined by SDS-PAGE
Description The rat LAG3 (Q5BK54)(Met1-Leu442) was expressed with a polyhistidine tag at the C-terminus
Host Species Rat
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Leu442
Product Background LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.Immune CheckpointImmune Checkpoint TargetsCo-inhibitory Immune Checkpoint Targets ImmunotherapyCancer ImmunotherapyTargeted Therapy
Uniprot Number Q5BK54
Terminal Gly 24
Bioactivity Please contact us for detailed information