Recombinant JAM-A Protein, Mouse (Fc Tag) Recombinant Proteins The mouse F11R (NP_766235.1) extracellular domain (Met 1-Ala 242) was fused with the Fc region of human IgG1 at the C-terminus The secreted recombinant mouse F11R/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 457a.a and has a predicted molecular weight of 50.2 kDa. rmF11R/Fc monomer migrates as an is approximately 57 kDa band in SDS-PAGE under reducing conditions, with ~10% free Fc fragment.
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Formulation: The secreted recombinant mouse F11R/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 457a.a and has a predicted molecular weight of 50.2 kDa. rmF11R/Fc monomer migrates as an is approximately 57 kDa band in SDS-PAGE under reducing conditions, with ~10% free Fc fragment.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant JAM-A Protein, Mouse (Fc Tag)

Formulation: Recombinant JAM-A Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant JAM-A Protein, Mouse (Fc Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant JAM-A Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The secreted recombinant mouse F11R/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 457a.a and has a predicted molecular weight of 50.2 kDa. rmF11R/Fc monomer migrates as an is approximately 57 kDa band in SDS-PAGE under reducing conditions, with ~10% free Fc fragment.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 94% as determined by SDS-PAGE
Description The mouse F11R (NP_766235.1) extracellular domain (Met 1-Ala 242) was fused with the Fc region of human IgG1 at the C-terminus
Host Species Mouse
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Ala 242
Product Background Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
Memo 9130004G24 Protein, Mouse;AA638916 Protein, Mouse;ESTM33 Protein, Mouse;JAM Protein, Mouse;JAM-1 Protein, Mouse;JAM-A Protein, Mouse;Jcam Protein, Mouse;Jcam1 Protein, Mouse;Ly106 Protein, Mouse
Terminal Lys 27
Bioactivity Please contact us for detailed information