Recombinant JAM-A Protein, Rat (Fc Tag) Recombinant Proteins The rat F11R () was expressed, fused with the Fc region of human IgG1 at the C-terminus The recombinant rat F11R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 453a.a and has a predicted molecular weight of 49.9 kDa. The apparent molecular weight of the protein is approximately 60 kDa in SDS-PAGE under reducing conditions.
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Formulation: The recombinant rat F11R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 453a.a and has a predicted molecular weight of 49.9 kDa. The apparent molecular weight of the protein is approximately 60 kDa in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant JAM-A Protein, Rat (Fc Tag)

Formulation: Recombinant JAM-A Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant JAM-A Protein, Rat (Fc Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant JAM-A Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The recombinant rat F11R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 453a.a and has a predicted molecular weight of 49.9 kDa. The apparent molecular weight of the protein is approximately 60 kDa in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 96% as determined by SDS-PAGE
Description The rat F11R () was expressed, fused with the Fc region of human IgG1 at the C-terminus
Host Species Rat
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Product Background Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
Uniprot Number Q9JHY1
Terminal Lys 27
Bioactivity Please contact us for detailed information