Recombinant IL-13 Protein, Cynomolgus Recombinant Proteins The Cynomolgus (Macaca fascicularis) IL13 (ABG75889.1) (Met 1-Asn 132) precursor was expressed The recombinant Cynomolgus IL13 consists of 112a.a and has a calculated molecular weight of 12.3 kDa as estimated by SDS-PAGE under reducing conditions.
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Formulation: The recombinant Cynomolgus IL13 consists of 112a.a and has a calculated molecular weight of 12.3 kDa as estimated by SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant IL-13 Protein, Cynomolgus

Formulation: Recombinant IL-13 Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant IL-13 Protein, Cynomolgus
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant IL-13 Protein was lyophilized from sterile PBS, pH 7.4.1
Molecular Weight The recombinant Cynomolgus IL13 consists of 112a.a and has a calculated molecular weight of 12.3 kDa as estimated by SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 85% as determined by SDS-PAGE
Description The Cynomolgus (Macaca fascicularis) IL13 (ABG75889.1) (Met 1-Asn 132) precursor was expressed
Host Species Cynomolgus
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Asn 132
Product Background Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy
Terminal Ser 21
Bioactivity Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-8 ng/mL.