Recombinant FLT1 Protein, Rat (His Tag) Recombinant Proteins The rat FLT1 (P53767) (Met1-Glu758) was expressed with a polyhistidine tag at the C-terminus The recombinant rat FLT1 comprises 747a.a and predicts a molecular weight of 84 kDa. The apparent molecular weight of the recombinant protein is approximately 108-114 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The recombinant rat FLT1 comprises 747a.a and predicts a molecular weight of 84 kDa. The apparent molecular weight of the recombinant protein is approximately 108-114 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant FLT1 Protein, Rat (His Tag)

Formulation: Recombinant FLT1 Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant FLT1 Protein, Rat (His Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant FLT1 Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The recombinant rat FLT1 comprises 747a.a and predicts a molecular weight of 84 kDa. The apparent molecular weight of the recombinant protein is approximately 108-114 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 90% as determined by SDS-PAGE
Description The rat FLT1 (P53767) (Met1-Glu758) was expressed with a polyhistidine tag at the C-terminus
Host Species Rat
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Glu758
Product Background Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy
Uniprot Number P53767
Terminal Tyr 23
Bioactivity Measured by its binding ability in a functional ELISA.Immobilized ratFLT1-His at 10 ug/ml (100 ul/well) can bind biotinylated mouse VEGFD-Fc with a linear range of 0.125-2.0 ug/ml.