Recombinant FLRT2 Protein, Mouse (His Tag) Recombinant Proteins The mouse FLRT2 (Q8BLU0) (Met1-Ser539) was expressed with a C-terminal polyhistidine tag The recombinant mouse FLRT2 comprises 515a.a and has a predicted molecular weight of 57.6 kDa. The apparent molecular weight of the protein is approximately 68-78 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The recombinant mouse FLRT2 comprises 515a.a and has a predicted molecular weight of 57.6 kDa. The apparent molecular weight of the protein is approximately 68-78 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant FLRT2 Protein, Mouse (His Tag)

Formulation: Recombinant FLRT2 Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant FLRT2 Protein, Mouse (His Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant FLRT2 Protein was lyophilized from sterile PBS, pH 7.4.1
Molecular Weight The recombinant mouse FLRT2 comprises 515a.a and has a predicted molecular weight of 57.6 kDa. The apparent molecular weight of the protein is approximately 68-78 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 95% as determined by SDS-PAGE
Description The mouse FLRT2 (Q8BLU0) (Met1-Ser539) was expressed with a C-terminal polyhistidine tag
Host Species Mouse
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Ser539
Product Background Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vinculin. FLRT1, FLRT2, and FLRT3, the three genes encode putative type I transmembrane proteins, each containing 1 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT family members may function in cell adhesion and/or receptor signalling. Each member of the FLRT family has a distinct, highly regulated expression pattern, as was seen for the NLRR family. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting that interaction with FGF signalling may be a general property of FLRT proteins. All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. FLRT proteins have a dual role, promoting FGF signalling and modulating homotypic cell adhesion. FLRT2 played critical roles in craniofacial development, and it was also present in the vomero-nasal organ, mandibular primodia, and the posterior aspects of the unfused and fused secondary palatal shelves.
Memo FLRT2 Protein, Mouse
Uniprot Number Q8BLU0
Terminal Cys 36
Bioactivity Measured by the ability of the immobilized protein to support the adhesion of Neuro‑2A mouse neuroblastoma cells.When cells are added to coated plates(5ug/mL,100uL/well), approximately 50%-70% will adhere after 1 hour at 37℃.