Recombinant EGFR Protein, Human (His Tag) Recombinant Proteins The extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was expressed with a C-terminal polyhistidine tag The recombinant human EGF receptor consists of 630a.a and has a calculated molecular weight of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human EGF receptor consists of 630a.a and has a calculated molecular weight of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant EGFR Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-203172

Molecular Weight: The recombinant human EGF receptor consists of 630a.a and has a calculated molecular weight of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.

Formulation: Recombinant EGFR Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant EGFR Protein, Human (His Tag)
Molecular Weight The recombinant human EGF receptor consists of 630a.a and has a calculated molecular weight of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Ser 645
Bioactivity Measured by its ability to bind human EGF in a functional ELISA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant EGFR Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Description The extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was expressed with a C-terminal polyhistidine tag
Product Background As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy
Product Memo ERBB Protein, Human;ERBB1 Protein, Human;HER1 Protein, Human;mENA Protein, Human;NISBD2 Protein, Human;PIG61 Protein, Human
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Leu 25
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use