Recombinant E1 Ubiquitin Activating Enzyme Protein, Human (His & GST Tag) Others The human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant human UBA1/GST chimera consists of 1294a.a and has a calculated molecular weight of 146 KDa. It migrates as an approximately 130 KDa band in SDS-PAGE under reducing conditions.
$ $99 In stock
Formulation: The recombinant human UBA1/GST chimera consists of 1294a.a and has a calculated molecular weight of 146 KDa. It migrates as an approximately 130 KDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Recombinant E1 Ubiquitin Activating Enzyme Protein, Human (His & GST Tag) -

Recombinant E1 Ubiquitin Activating Enzyme Protein, Human (His & GST Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog Number: BT-203232

Molecular Weight: The recombinant human UBA1/GST chimera consists of 1294a.a and has a calculated molecular weight of 146 KDa. It migrates as an approximately 130 KDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant E1 Ubiquitin Activating Enzyme Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 7.4, 10% gly, 0.5mM GSH1

Source: Baculovirus-Insect Cells

Product Name Recombinant E1 Ubiquitin Activating Enzyme Protein, Human (His & GST Tag)
Molecular Weight The recombinant human UBA1/GST chimera consists of 1294a.a and has a calculated molecular weight of 146 KDa. It migrates as an approximately 130 KDa band in SDS-PAGE under reducing conditions.
AA Sequence Ser 2-Arg 1058
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant E1 Ubiquitin Activating Enzyme Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 7.4, 10% gly, 0.5mM GSH1
Host Species Homo sapiens (Human)
Description The human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Product Background UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Defects in UBA1 can cause spinal muscular atrophy X-linked type 2 (SMAX2), also known as X-linked lethal infantile spinal muscular atrophy, distal X-linked arthrogryposis multiplex congenita or X-linked arthrogryposis type 1 (AMCX1). Spinal muscular atrophy refers to a group of neuromuscular disorders characterized by degeneration of the anterior horn cells of the spinal cord, leading to symmetrical muscle weakness and atrophy. SMAX2 is a lethal infantile form presenting with hypotonia, areflexia, and multiple congenital contractures.
Product Memo A1S9 Protein, Human;A1S9T Protein, Human;A1ST Protein, Human;AMCX1 Protein, Human;CFAP124 Protein, Human;CTD-2522E6.1 Protein, Human;GXP1 Protein, Human;POC20 Protein, Human;SMAX2 Protein, Human;UBA1A Protein, Human;UBE1 Protein, Human;UBE1X Protein,
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Jul 26 2021