Recombinant Contactin 3 Protein, Rat (Fc Tag) Recombinant Proteins The rat CNTN3 (Met1-Gly1001) was expressed with the Fc region of human IgG1 at the C-terminus The recombinant rat CNTN3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 1224a.a and has a predicted molecular weight of 134.8 kDa. The apparent molecular weight of the protein is approximately 135 kDa in SDS-PAGE under reducing conditions.
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Formulation: The recombinant rat CNTN3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 1224a.a and has a predicted molecular weight of 134.8 kDa. The apparent molecular weight of the protein is approximately 135 kDa in SDS-PAGE under reducing conditions.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Contactin 3 Protein, Rat (Fc Tag)

Formulation: Recombinant Contactin 3 Protein was lyophilized from sterile PBS, pH 7.41

Source: HEK293 Cells

Product Name Recombinant Contactin 3 Protein, Rat (Fc Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant Contactin 3 Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The recombinant rat CNTN3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 1224a.a and has a predicted molecular weight of 134.8 kDa. The apparent molecular weight of the protein is approximately 135 kDa in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 85% as determined by SDS-PAGE
Description The rat CNTN3 (Met1-Gly1001) was expressed with the Fc region of human IgG1 at the C-terminus
Host Species Rat
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Gly1001
Product Background Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 198s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.
Terminal Glu 20
Bioactivity Please contact us for detailed information