Recombinant CPLX2 Protein, Human (His Tag) Recombinant Proteins The human CPLX2 (Q6PUV4-1) (Asp 2-Lys 134) was expressed, with a polyhistide tag at the N-terminus The recombinant human CPLX2 consists of 144a.a and has a calculated molecular weight of 16.8 kDa. It migrates as an 21 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human CPLX2 consists of 144a.a and has a calculated molecular weight of 16.8 kDa. It migrates as an 21 kDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant CPLX2 Protein, Human (His Tag)

Formulation: Recombinant CPLX2 Protein was lyophilized from sterile PBS, pH 7.41

Source: E. coli

Product Name Recombinant CPLX2 Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant CPLX2 Protein was lyophilized from sterile PBS, pH 7.41
Molecular Weight The recombinant human CPLX2 consists of 144a.a and has a calculated molecular weight of 16.8 kDa. It migrates as an 21 kDa band in SDS-PAGE under reducing conditions.
Purity Greater than 90% as determined by SDS-PAGE
Description The human CPLX2 (Q6PUV4-1) (Asp 2-Lys 134) was expressed, with a polyhistide tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Asp 2-Lys 134
Product Background Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target SNARE complexes. Complexin 1 (CX1) and complexin 2 (CX2) are presynaptic proteins that modulate neurotransmitter release and are used as markers of inhibitory and excitatory synapses, respectively. CPLX2 is localized in pre-synaptic terminals in mature brain. The G71-P89 region of CPLX2 is essential and sufficient for preferential axonal distribution. CPLX2 participates in the Ca(2+)-sensitive regulatory pathway for zymogen granule exocytosis. Complexin-2 is a key player in normal neurological function, and its downregulation could lead to changes in neurotransmitter release sufficient to cause significant behavioural abnormalities such as depression. It is involved in synaptogenesis and the modulation of neurotransmitter release.
Memo 921-L Protein, Human;CPX-2 Protein, Human;CPX2 Protein, Human;Hfb1 Protein, Human
Uniprot Number Q6PUV4
Terminal Met
Bioactivity Please contact us for detailed information