Recombinant CDNF Protein, Human (Fc Tag) Recombinant Proteins The human CDNF (NP_001025125.2) (Met1-Leu187) was expressed with the Fc region of human IgG1 at the C-terminus The recombinant human CDNF consists 401a.a and predicts a molecular weight of 45.2 kDa.
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Formulation: The recombinant human CDNF consists 401a.a and predicts a molecular weight of 45.2 kDa.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant CDNF Protein, Human (Fc Tag)

Formulation: Recombinant CDNF Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant CDNF Protein, Human (Fc Tag)
Product Type Recombinant Protein
Source HEK293 Cells
Formulation Recombinant CDNF Protein was lyophilized from sterile PBS, pH 7.4.1
Molecular Weight The recombinant human CDNF consists 401a.a and predicts a molecular weight of 45.2 kDa.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method
Purity Greater than 95% as determined by SDS-PAGE.
Description The human CDNF (NP_001025125.2) (Met1-Leu187) was expressed with the Fc region of human IgG1 at the C-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Leu187
Product Background Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
Memo ARMETL1 Protein, Human
Terminal Gln 25
Bioactivity Please contact us for detailed information