Recombinant CCL28 Protein, Human (His Tag) Recombinant Proteins The human CCL28 (NP_683513.1) (Ile23-Tyr127) was expressed with a polyhistidine tag at the N-terminus The recombinant human CCL28 consists of 121a.a and predicts a molecular weight of 14.2 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human CCL28 consists of 121a.a and predicts a molecular weight of 14.2 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant CCL28 Protein, Human (His Tag)

Formulation: Recombinant CCL28 Protein was lyophilized from sterile PBS, pH 7.4.1

Source: E. coli

Product Name Recombinant CCL28 Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant CCL28 Protein was lyophilized from sterile PBS, pH 7.4.1
Molecular Weight The recombinant human CCL28 consists of 121a.a and predicts a molecular weight of 14.2 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
Purity Greater than 95% as determined by SDS-PAGE
Description The human CCL28 (NP_683513.1) (Ile23-Tyr127) was expressed with a polyhistidine tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Ile23-Tyr127
Product Background CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR1 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and to lactating mammary gland as well. In addition, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues and secretions suggest that this protein plays an important role in innate immune protection of the epithelial surfaces. CCL28 is a human chemokine constitutively expressed by epithelial cells in diverse mucosal tissues and is known to attract a variety of immune cell types including T-cell subsets and eosinophils. Elevated levels of CCL28 have been found in the airways of individuals with asthma, and previous studies have indicated that CCL28 plays a vital role in the acute development of post-viral asthma. CCL28 presents a novel target for the development of alternative asthma therapeutics. The dental decay of children leads to the secretion of chemokine CCL28, which promotes the secretion of sIgA in saliva. CC chemokine ligand28 (CCL28) has been reported as a severity marker in atopic dermatitis.
Memo CCK1 Protein, Human;MEC Protein, Human;SCYA28 Protein, Human
Terminal His
Bioactivity Please contact us for detailed information