Recombinant BLVRB Protein, Human (His Tag) Recombinant Proteins The human BLVRB (P30043) (Ala 2-Gln 206) was expressed, with a polyhistide tag at the N-terminus The recombinant human BLVRB consisting of 216a.a and has a calculated molecular weight of 23.5 kDa. It migrates as a kDa band in SDS-PAGE under reducing conditions as predicted.
$ $99 In stock
Formulation: The recombinant human BLVRB consisting of 216a.a and has a calculated molecular weight of 23.5 kDa. It migrates as a kDa band in SDS-PAGE under reducing conditions as predicted.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant BLVRB Protein, Human (His Tag)

Formulation: Recombinant BLVRB Protein was lyophilized from sterile PBS, 0.02% Brij35, 10% glycerol, pH 7.51

Source: E. coli

Product Name Recombinant BLVRB Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant BLVRB Protein was lyophilized from sterile PBS, 0.02% Brij35, 10% glycerol, pH 7.51
Molecular Weight The recombinant human BLVRB consisting of 216a.a and has a calculated molecular weight of 23.5 kDa. It migrates as a kDa band in SDS-PAGE under reducing conditions as predicted.
Purity Greater than 97% as determined by SDS-PAGE
Description The human BLVRB (P30043) (Ala 2-Gln 206) was expressed, with a polyhistide tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Ala 2-Gln 206
Product Background Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step in heme degradation by reducing the γ-methene bridge of the open tetrapyrrole, biliverdin IXα, to bilirubin with the concomitant oxidation of a β-nicotinamide adenine dinucleotide (NADH) or β-nicotinamide adenine dinucleotide phosphate (NADPH) cofactor. It is now recognized that human BVR (hBVR) is a dual-specificity kinase (Ser / Thr and Tyr) upstream activator of the insulin/insulin growth factor-1 (IGF-1) and mitogen-activated protein kinase (MAPK) signaling pathways. Human BVR (hBVR) is essential for MAPK-extracellular signal-regulated kinase (ERK)1/2 (MEK)-eukaryotic-like protein kinase (Elk) signaling and has been identified as the cytoplasm-nuclear heme transporter of ERK1/2 and hematin, the key components of stress-responsive gene expression.
Memo BVRB Protein, Human;FLR Protein, Human;HEL-S-10 Protein, Human;SDR43U1 Protein, Human
Uniprot Number P30043
Terminal Met
Bioactivity Please contact us for detailed information